The relation between total daily caloric intake and blood pressure.

BACKGROUND: More caloric intake and less physical activity engenders more obesity and any degree of weight gain even to the level that is not defined as overweight is associated with an increase of hypertension. It is not defined that if total caloric intake irrespective of weight gain had any effect on blood pressure. This is an observational study about the relationships between blood pressure and daily calorie intake in 1,061 female and 890 male aged 20-51 years. METHOD: Relation of daily total caloric intake and blood pressure in normotensive and hypertensive samples. Dietary data were obtained from a food-frequency questionnaire which was analyzed by software designed for Iranian foods designed by Isfahan cardiovascular research center to calculate the total daily caloric intake. Blood pressure was measured three times by korotkoff method. The relation between daily total caloric intake and blood pressure was analyzed by general linear regression and logistic regression. RESULTS: Generalized linear regression revealed no significant relation between either systolic or diastolic blood pressure and daily total caloric intake irrespective of normal or abnormal blood pressure. This association remained non-significant even after adjustment for body mass index (BMI) p<0.05. Logistic regression analysis revealed that there is no significant relation between total caloric intake and existence of systolic or diastolic hypertension OR=1, p>0.05. After adjustment for BMI also, there was no significant relation between these two parameters OR=1, p>0.05. CONCLUSION: Usual relation between caloric intake and blood pressure in obese may be due to insulin resistance induced by obesity. So total daily caloric intake in general population had no significant effect on blood pressure and on development of hypertension when the effect of obesity is adjusted.

Electrocardiographic and angiographic corelation of positive T-wave in V1 and coronary stenosis in patients with stable angina

During myocardial infarction ECG could determine the anatomic territory of necrotic myocardium. In stable angina the anatomic territory of ischemic myocardium is less correlated to ECG changes. In this study the correlation between positive T-Wave in lead V1 and the anatomic position of coronary arteries and the severity of stenotic lesion are investigated in patients with stable angina Method: this is a cross sectional analytical prospective study. The study was done in chamran hospital of Isfahan. Two hundred patients were involved in these study. 100 patients with negative T-wave in V1 as control group and hundred patients with positive T-wave in V1 as cases. All patient were angiographied. The cine films were interpreted by two cardiologists. Of patient who had positive T-wave in V1 84%, had a significant lesion on one or more of their coronary arteries. Patients with negative T-wave on V1 Only 54% had significant coronary lesion [P < 0.005]. Patients who had a positive T-Wave in V1 in 85% of cases, LAD, in 76.1% of cases, RCA and in 57.1% of cases the LCX had significant stenosis [P < 0.005]. Positive T wave on V1 predict more significant stenotic lesion of coronary arteries. But its correlation with anatomic location is more controversial

Cardiac rehabilitation comparison of its effect on improvement of ejection fraction and functional capacity in men and women

Background and Objective: Exercise intolerance is one of the main features of ischemic heart disease. Patients always restrict their activities because of early fatigue and low functional capacity. Cardiac rehabilitation and supervised exercise have positive effect on these patients functional capacity. This may be due to improvement in cardiac performance or reconditioning by alteration in muscular metabolism

Methods: Two hundred and three patients who were referred by their physicians for cardiac rehabilitation after myocardial infarction or CABG entered the study. Forty patients were female. Exercise test and echocardiography were performed in all patients before and after rehabilitation course. The cardiac rehabilitation's exercise program composed of 24 sessions. Each session consisted of one hour of aerobic exercise [10 min warm up, 10 min cool down and 40 min isotonic exercise]

Results: Ejection fraction and functional capacity were increased in both female and male patients after the study period. The differences were significant by paired test in each group [p<0.001]. The difference between male and female was significant for functional capacity and the increase in FC was greater for male patients [p<0.02]. There was no significant increase in EF for female patients [p<0.05]. In male patients EF was increased significantly [p<0.001]

Conclusion: Women are fewer participants in cardiac rehabilitation although they appear to benefit equally well. Thus referral to cardiac rehabilitation programs should be advocated for both men and women and should not be limited by sex